B. C. and E. A. were both on a long-term research team. This research project aimed to develop a safe and effective treatment for erectile dysfunction in the Chinese public.
This study was done to evaluate the safety and effectiveness of the new phosphodiesterase 5 inhibitor Cialis® in the Chinese population. This study was approved by the Research Ethics Committee for the Chinese University of Hong Kong and the Research Ethics Committee of the Shanghai Medical University in China. The study was conducted in accordance with the ethical principles of the Declaration of Helsinki. The study was conducted at the Department of Pharmaceutical Research, the Institute for Drug Discovery, and the Department of Pharmaceutical Sciences, Shanghai University of Food and Drug Administration (SPU), Shanghai, China.
The study protocol was approved by the Institutional Review Board, Shanghai University of Food and Drug Administration (IRB No. 201241101).
Cialis® was administered orally as a single daily dose with or without food. The effect of the drug on the sexual function of patients was studied in a double-blind, randomized, placebo-controlled trial, in which 36 male patients who did not meet the inclusion criteria were administered Cialis® at a dose of 20 mg or 40 mg three times daily. The drug was administered for 5 days after the end of treatment. Patients with erectile dysfunction had to discontinue the medication, and they were also advised not to use the drug for at least 5 days. In this study, patients with erectile dysfunction who experienced a spontaneous erection at the time of study were not allowed to resume the medication. The patients who did not experience erection at the time of study were also advised to stop the drug. The duration of Cialis® administration was approximately 3 weeks.
Erectile dysfunction was defined as the inability to achieve or maintain an erection for more than 5 min. This study included patients with erectile dysfunction who were taking tadalafil and who had a history of erectile dysfunction. Patients with erectile dysfunction who had a history of priapism and/or priapism and/or a history of priapism or priapism and/or a history of penile bleeding or priapism were not permitted to take Cialis®. Patients with a history of priapism and/or priapism and/or a history of penile bleeding or priapism were not permitted to take Cialis®.
The study was approved by the Medical Ethics Committee of the Shanghai Medical University in China and the Research Ethics Committee of the Shanghai University of Food and Drug Administration in China. The Institutional Review Board and the Institutional Review Board of the Shanghai Medical University approved this study.
1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
Cialis (tadalafil) can interact with certain foods and beverages, possibly altering its effectiveness or increasing thesharing of the interaction.
Nitrates (e.
Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Cialis use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
Show Moreuspressile Dose Cialis Daily Cialis Daily (Tadalafil) 5mg Daily Capsule| Cigars | 5mg, 10mg |
| 20mg | Tildenafil (generic Cialis) |
| 25mg | Vardenafil (generic Cialis) |
| 50mg | Sildenafil (generic Cialis) |
In addition, be sure to provide your doctor with a list of all the products you use (including all brand names and generic). This will allow them to assess your condition and ensure it is suitable for you.
In addition, let your doctor know if you have recently had a heart attack or stroke, if you have low blood pressure, if you have low blood pressure that is uncontrolled by nitrates, if you have a liver disease, if you have kidney disease, if you are history of heart attack or stroke, and if you are history of women who have sex with men.
Nonprescription Cialis Daily (Tadalaf) 10mg, 20mg, 25mg, 50mg, 100mgThe daily (20mg, 50mg, and 100mg) and the weekly (20mg, 25mg, and 50mg) are all prescribed to be taken on an as-needed basis. They are intended to be taken on an empty stomach, with or without food. It is recommended to take Cialis at approximately the same time each day. This makes it more likely that you will get side effects at some time in your health.
Cialis is a medication that is used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). It contains the active ingredient tadalafil and is prescribed for men who have difficulty getting or keeping an erection.
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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Cialis use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
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